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Sweetman (ed.), Martindale 35: The Complete Drug Reference. The peak of mebhydrolin napadisylate was not interfered by those of possible degradation products. The drug was subjected to acidic and alkaline hydrolysis, oxidation, dry heat, and UV treatment. The detection limit and quantification limit were 18.5 and 55.5 ng/spot, respectively. The RSD of repeatability and intermediate precision were found to be less than 2%, whereas the mean of the recovery data was 99.3–100.8%.

Good linearity was achieved in the concentration range 600–1600 ng/spot. The method was validated for specificity, linearity, accuracy, precision, and robustness. Quantitative evaluation was performed by measuring the absorbance reflectance of the analyte spots at 287 nm. After extraction of the analyte with a mixture of methanol and NH 4 OH 25% (100:1.5, v/v), the extracts were spotted on precoated HPTLC silica gel F254 plates, which were developed with a mixture of methanol and ethyl acetate (1:1, v/v). Mayes, PhD, DSc Editor edisi bahasa Indonesia:, MD,dr.A simple and rapid high-performance thin-layer chromatography (HPTLC) densitometric method has been developed for the determination of mebhydrolin napadisylate in tablets. Where to download ebooks for ebook, psycho cybernetics ebook free.

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